Searchable abstracts of presentations at key conferences in endocrinology

ea0081p587 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

GLP-1 and glucagon depict complementary actions on visceral adipose tissue that could mediate metabolic shifts towards catabolism

Morais Tiago , Seabra Alexandre , Patricio Barbara , Guimaraes Marta , Nora Mario , Oliveira Pedro , Alves Marco , Monteiro Mariana

Visceral adipose tissue (VAT) metabolic fingerprints differ according to the individual’s BMI and glycemic status. GLP-1 and Glucagon are two hormones that participate in energy homeostasis and glycemic control. Dual GLP-1/Glucagon agonists are a drug class under development for obesity and diabetes treatment. Although the pancreas and the liver are considered major GLP-1 and glucagon targets, these hormones act in other tissues, which could contribute for its effects on ...